Oprah told her staff of her decision during a company meeting on Thursday afternoon. The president of Harpo Studios notified media partners later Thursday.
She is expected to make a public announcement on "The Oprah Winfrey Show" on Friday.
The sun will set on the Oprah show as its 25th season draws to a close on September 9, 2011.
Back in January of 2008, Oprah announced she was launching OWN -- The Oprah Winfrey Network.
It was widely expected that the TV talk queen would stop doing her syndicated program in September 2011 to focus on the cable network.
That show was renamed "The Oprah Winfrey Show" and launched on September 8, 1986.
A year later, Winfrey established Harpo and her talk show went into syndication. In 1990, Winfrey opened Harpo Studios in Chicago's West Loop neighborhood.
The president of Harpo, Inc. issued a statement to stations that carry the Oprah show about her announcement.
Oprah is seen every weekday at 4:00 on Channel 7.
Copyright ©2009 WABC-TV/DT.
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